The idea for a Hispanic women's leadership group originated in 1987, when a small group of Hispanic women in Houston planned a women's conference. The Hispanic Women's Leadership Conference Committee's March conference, held in conjunction with the YWCA, was a success. In June 1988, Hispanic Women in Leadership was formed as a separate, nonprofit, tax exempt organization. The organization has grown from the approximately twenty original members to over two hundred, the majority of whom are professional Hispanic women. Members include doctors, lawyers, accountants, educators, media representatives and other professionals who provide positive role models to women and girls.

Hispanic Women in Leadership's main goal is to promote leadership skills among Hispanic women in Houston. In conjunction with this goal, the organization promotes education of Hispanic women and girls, identifies successful role models, develops a network of professional women, and encourages Hispanic women to embrace and celebrate their cultural heritage.

Hispanic Women in Leadership's major activity is their annual conference, held each spring in Houston. These conferences, which have grown over the years, have themes relevant to Hispanic women. They feature local and national educators and professional women and men who present workshops on issues such as the glass ceiling in the workplace and child care. The conferences raise money for scholarships to deserving young Hispanic women. In addition to the annual conference, Hispanic Women in Leadership also sponsors other fundraisers, such as fashion shows and garage sales.